From: Amazon

Wesley Snipes returns as Blade, the Marvel Comics character he vividly brought to life in the 1998 film. The blood coursing through Blade's veins is half-human, half-vampire, and is the result of a vampire attack on his mother prior to his birth. Blade is one of a kind, he has all the strengths of vampires but none of their weaknesses, such as exposure to sunlight. His world is filled with vampires he hates and he makes it his purpose in life to rid the world of their terror. The film was preceeded by Blade II and followed by Blade: Trinity.

Blade (Wesley Snipes) is the vampire-loathing daywalker. Although he is half-vampire, he has learned to control his thirst and dedicates his life to protecting humans from the bloodsuckers. But now Blade has a new enemy, an even more deadly breed of vampires known as Reapers who kill both humans and vampires. The old vampires approach Blade to form an alliance and reunited with Whistler (Kris Krisofferson), they lead an elite vampire team into battle with the Reapers.